CEO Guide to Site Selection



CEO Rank on Best & Worst States for Business


The Geo-Resolution 2021 conference helped the Show-Me State double down on its thriving geospatial analysis and cybersecurity sectors. The National Geospatial-Intelligence Agency, which broke ground on its new western regional headquarters in St. Louis in 2016, is scheduled to open in 2025. Several prominent geospatial companies have opened new offices and facilities in the region. In other industries, Diode Dynamics, TierPoint and La-Z-Boy announced projects here in 2021.

“Covid-19 had an overwhelming impact on businesses and communities across the state, but our economy continues to come back strong. We have made great progress in a short amount of time, and we must remain vigilant in our efforts and ensure our small businesses have the support they need to recover and succeed.”
Mike Parson


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top corporate income tax

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on the Tax Foundation’s State Business Tax Climate Index ranking


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of students graduated high school in 2019

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of adults age 25 and older have a bachelor’s degree or higher


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increase between 2010 and 2020


Missouri Works: Offers access to capital through with- holdings or tax credits to embark on facility expansions and create jobs.

Missouri One Start: A new tool to help businesses re- cruit, onboard and train large numbers of job applicants during major expansions through customized training solutions.

BUILD Program: Offers financial incentives, including low interest loans, for the location or expansion of large business projects through the issuance of tax-exempt revenue bonds.

Missouri Works–Deal Closing Fund: A negotiating tool to close deals by granting tax credits up front during a business expansion, rather than over a multi- year period.


Missouri Department of Economic Development

Missouri Partnership

Missouri One Start

Springfield Regional Economic Partnership

Economic Development Corporation of Kansas City

St. Louis Economic Development Partnership


The National Security Crossroads is a multi-state initiative with Kansas that aims to raise awareness of and facilitate collaboration and efficiencies within national security missions to the Heartland region. The crossroads area is home to seven major military bases and 11 national security installations. The program will facilitate workforce, talent growth and collaboration between installations to educate legislators and others in the region on the value of the industry.


  • Anheuser-Busch announced in April 2021 it will invest $100 million in a grain repurposing facility at its St. Louis campus and create 50 jobs.
  • Canadian logistic company Metro Supply Chain Group announced in June 2021, it will locate its third U.S. fulfill- ment center in Kansas city and create up to 100 jobs.
  • Deli Star Corporation announced in July 2021 plans to locate its new headquarters in St. Louis. The $99 million capital investment will bring 475 jobs to the region.
  • Diode Dynamics announced in August 2021 the construction of a new headquarters in St. Charles.
  • Pet supply company Chewy cut the ribbon on a new ecommerce fulfillment center in Belton in August 2021 that will eventually create 1,000 jobs.
  • La-Z-Boy announced in August 2021 it will invest an additional $30 million in its manufacturing facility in Neosho.
  • MSI announced in September 2021 plans to launch a new showroom and distribution facility in St. Louis.
  • TierPoint announced in September 2021 a $20 million expansion in the St. Louis region.


10 Fortune 500 companies are headquartered in the state:

  • Centene Corporation 
  • Emerson Electric
  • Reinsurance Group of America 
  • O’Reilly Automotive
  • Edward Jones Investments 
  • Graybar Electric
  • Olin 
  • Ameren
  • Post Holdings 
  • Peabody Energy